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The intersection of amyloid beta and tau in glutamatergic synaptic dysfunction and collapse in Alzheimer’s disease

The synaptic connections that form between neurons during development remain plastic and able to adapt throughout the lifespan, enabling learning and memory. However, during aging and in particular in neurodegenerative diseases, synapses become dysfunctional and degenerate, contributing to dementia....

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Detalhes bibliográficos
Main Authors: Crimins, Johanna L., Pooler, Amy, Polydoro, Manuela, Luebke, Jennifer I., Spires-Jones, Tara L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735866/
https://ncbi.nlm.nih.gov/pubmed/23528367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.arr.2013.03.002
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