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The intersection of amyloid beta and tau at synapses in Alzheimer’s disease

The collapse of neural networks important for memory and cognition, including death of neurons and degeneration of synapses, causes the debilitating dementia associated with Alzheimer’s disease (AD). We suggest that synaptic changes are central to the disease process. Amyloid beta and tau form fibri...

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Autores principales: Spires-Jones, Tara L, Hyman, Bradley T
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135182/
https://ncbi.nlm.nih.gov/pubmed/24853936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.05.004
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