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Soluble forms of tau are toxic in Alzheimer’s disease
Accumulation of neurofibrillary tangles (NFT), intracellular inclusions of fibrillar forms of tau, is a hallmark of Alzheimer Disease. NFT have been considered causative of neuronal death, however, recent evidence challenges this idea. Other species of tau, such as soluble misfolded, hyperphosphoryl...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3460520/ https://ncbi.nlm.nih.gov/pubmed/23029602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2478/s13380-012-0032-y |
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