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Propagation of tau pathology in a model of early Alzheimer’s disease
Neurofibrillary tangles advance from layer II of the entorhinal cortex (EC-II) toward limbic and association cortices as Alzheimer disease (AD) evolves. However, the mechanism involved in this hierarchical pattern of disease progression is unknown. We describe a transgenic mouse model in which overe...
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| 主要な著者: | , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3292759/ https://ncbi.nlm.nih.gov/pubmed/22365544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2011.11.033 |
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