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Propagation of tau pathology in a model of early Alzheimer’s disease
Neurofibrillary tangles advance from layer II of the entorhinal cortex (EC-II) toward limbic and association cortices as Alzheimer disease (AD) evolves. However, the mechanism involved in this hierarchical pattern of disease progression is unknown. We describe a transgenic mouse model in which overe...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2012
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3292759/ https://ncbi.nlm.nih.gov/pubmed/22365544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2011.11.033 |
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