Reversal of Neurofibrillary Tangles and Tau-Associated Phenotype in the rTgTauEC Model of Early Alzheimer's Disease

Neurofibrillary tangles (NFTs), a marker of neuronal alterations in Alzheimer's disease (AD) and other tauopathies, are comprised of aggregates of hyperphosphorylated tau protein. We recently studied the formation of NFTs in the entorhinal cortex (EC) and their subsequent propagation through ne...

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Hlavní autoři: Polydoro, Manuela, de Calignon, Alix, Suárez-Calvet, Marc, Sanchez, Laura, Kay, Kevin R., Nicholls, Samantha B., Roe, Allyson D., Pitstick, Rose, Carlson, George A., Gómez-Isla, Teresa, Spires-Jones, Tara L., Hyman, Bradley T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742920/
https://ncbi.nlm.nih.gov/pubmed/23946388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0881-13.2013
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