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Are Tangles as Toxic as They Look?

Neurofibrillary tangles are intracellular accumulations of hyperphosphorylated and misfolded tau protein characteristic of Alzheimer's disease and other tauopathies. Classic cross-sectional studies of Alzheimer patient brains showed associations of tangle accumulation with neuronal loss, synaps...

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Detalhes bibliográficos
Main Authors: Spires-Jones, Tara L., Kopeikina, Katherine J., Koffie, Robert M., de Calignon, Alix, Hyman, Bradley T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173560/
https://ncbi.nlm.nih.gov/pubmed/21638071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-011-9566-7
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