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Are Tangles as Toxic as They Look?
Neurofibrillary tangles are intracellular accumulations of hyperphosphorylated and misfolded tau protein characteristic of Alzheimer's disease and other tauopathies. Classic cross-sectional studies of Alzheimer patient brains showed associations of tangle accumulation with neuronal loss, synaps...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3173560/ https://ncbi.nlm.nih.gov/pubmed/21638071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-011-9566-7 |
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