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Monitoring protein aggregation and toxicity in Alzheimer’s disease mouse models using in vivo imaging
Aggregation of amyloid beta peptide into senile plaques and hyperphosphorylated tau protein into neurofibrillary tangles in the brain are the pathological hallmarks of Alzheimer’s disease. Despite over a century of research into these lesions, the exact relationship between pathology and neurotoxici...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3049845/ https://ncbi.nlm.nih.gov/pubmed/21163350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2010.12.009 |
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