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Rapid appearance and local toxicity of amyloid-β plaques in a mouse model of Alzheimer’s disease
Senile plaques accumulate over the course of decades in the brains of patients with Alzheimer’s disease. A fundamental tenet of the amyloid hypothesis of Alzheimer’s disease is that the deposition of amyloid-β precedes and induces the neuronal abnormalities that underlie dementia(1). This idea has b...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3264491/ https://ncbi.nlm.nih.gov/pubmed/18256671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06616 |
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