A Reporter of Local Dendritic Translocation Shows Plaque- Related Loss of Neural System Function in APP-Transgenic Mice

Although neuronal communication is thought to be summated within local dendritic segments, no technique is currently available to monitor activity in vivo at this level of resolution. To overcome this challenge, we developed an optical reporter of neuronal activity using the coding sequence of Venus...

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Detalhes bibliográficos
Main Authors: Meyer-Luehmann, Melanie, Mielke, Matthew, Spires-Jones, Tara L., Stoothoff, Will, Jones, Phill, Bacskai, Brian J., Hyman, Bradley T.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789808/
https://ncbi.nlm.nih.gov/pubmed/19812338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1948-09.2009
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