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A Reporter of Local Dendritic Translocation Shows Plaque- Related Loss of Neural System Function in APP-Transgenic Mice

Although neuronal communication is thought to be summated within local dendritic segments, no technique is currently available to monitor activity in vivo at this level of resolution. To overcome this challenge, we developed an optical reporter of neuronal activity using the coding sequence of Venus...

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Autors principals: Meyer-Luehmann, Melanie, Mielke, Matthew, Spires-Jones, Tara L., Stoothoff, Will, Jones, Phill, Bacskai, Brian J., Hyman, Bradley T.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789808/
https://ncbi.nlm.nih.gov/pubmed/19812338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1948-09.2009
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