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Rapid appearance and local toxicity of amyloid-β plaques in a mouse model of Alzheimer’s disease

Senile plaques accumulate over the course of decades in the brains of patients with Alzheimer’s disease. A fundamental tenet of the amyloid hypothesis of Alzheimer’s disease is that the deposition of amyloid-β precedes and induces the neuronal abnormalities that underlie dementia(1). This idea has b...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Meyer-Luehmann, Melanie, Spires-Jones, Tara L., Prada, Claudia, Garcia-Alloza, Monica, de Calignon, Alix, Rozkalne, Anete, Koenigsknecht-Talboo, Jessica, Holtzman, David M., Bacskai, Brian J., Hyman, Bradley T.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2008
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264491/
https://ncbi.nlm.nih.gov/pubmed/18256671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06616
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