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Amyloid Beta and Phosphorylated Tau Accumulations Cause Abnormalities at Synapses of Alzheimer’s disease Neurons

Amyloid Beta (Aβ) and hyperphosphorylated tau are hallmark lesions of Alzheimer disease (AD). However, the loss of synapses and dysfunctions of neurotransmission are more directly tied to disease severity. The role of these lesions in the pathoetiological progression of the disease remains contested...

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Detalles Bibliográficos
Publicado en:J Alzheimers Dis
Main Authors: Rajmohan, Ravi, Reddy, P. Hemachandra
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5793225/
https://ncbi.nlm.nih.gov/pubmed/27567878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-160612
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