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Amyloid Beta Impairs Mitochondrial Anterograde Transport and Degenerates Synapses in Alzheimer’s Disease Neurons
Loss of synapses and synaptic damage are the best correlates of cognitive decline identified in patients with Alzheimer’s disease (AD), and mitochondrial oxidative damage and synaptic pathology have been identified as early events in the progression of AD. The progressive accumulation of amyloid bet...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3042500/ https://ncbi.nlm.nih.gov/pubmed/21241801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2011.01.007 |
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