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Amyloid Beta Impairs Mitochondrial Anterograde Transport and Degenerates Synapses in Alzheimer’s Disease Neurons

Loss of synapses and synaptic damage are the best correlates of cognitive decline identified in patients with Alzheimer’s disease (AD), and mitochondrial oxidative damage and synaptic pathology have been identified as early events in the progression of AD. The progressive accumulation of amyloid bet...

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Autors principals: Calkins, Marcus J., Reddy, P. Hemachandra
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042500/
https://ncbi.nlm.nih.gov/pubmed/21241801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2011.01.007
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