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Mitochondria-Targeted Antioxidant SS31 Prevents Amyloid Beta-Induced Mitochondrial Abnormalities and Synaptic Degeneration in Alzheimer’s Disease

In neuronal systems, the health and activity of mitochondria and synapses are tightly coupled. For this reason, it has been postulated that mitochondrial abnormalities may, at least in part, drive neurodegeneration in conditions such as Alzheimer’s disease (AD). Mounting evidence from multiple Alzhe...

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Detalhes bibliográficos
Principais autores: Calkins, Marcus J., Manczak, Maria, Reddy, P. Hemachandra
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513393/
https://ncbi.nlm.nih.gov/pubmed/23226091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph5101103
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