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Amyloid-β and Mitochondria in Aging and Alzheimer’s Disease: Implications for Synaptic Damage and Cognitive Decline

This article reviews the role of amyloid-β (Aβ) and mitochondria in synaptic damage and cognitive decline found in patients with Alzheimer’s disease (AD). Recent molecular, cellular, animal model, and postmortem brain studies have revealed that Aβ and mitochondrial abnormalities are key factors that...

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Detalhes bibliográficos
Main Authors: Reddy, P. Hemachandra, Manczak, Maria, Mao, Peizhong, Calkins, Marcus J., Reddy, Arubala P., Shirendeb, Ulziibat
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059092/
https://ncbi.nlm.nih.gov/pubmed/20413847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2010-100504
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