Amyloid-β and Mitochondria in Aging and Alzheimer’s Disease: Implications for Synaptic Damage and Cognitive Decline

This article reviews the role of amyloid-β (Aβ) and mitochondria in synaptic damage and cognitive decline found in patients with Alzheimer’s disease (AD). Recent molecular, cellular, animal model, and postmortem brain studies have revealed that Aβ and mitochondrial abnormalities are key factors that...

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Hlavní autoři: Reddy, P. Hemachandra, Manczak, Maria, Mao, Peizhong, Calkins, Marcus J., Reddy, Arubala P., Shirendeb, Ulziibat
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059092/
https://ncbi.nlm.nih.gov/pubmed/20413847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2010-100504
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