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Amyloid-β and Mitochondria in Aging and Alzheimer’s Disease: Implications for Synaptic Damage and Cognitive Decline

This article reviews the role of amyloid-β (Aβ) and mitochondria in synaptic damage and cognitive decline found in patients with Alzheimer’s disease (AD). Recent molecular, cellular, animal model, and postmortem brain studies have revealed that Aβ and mitochondrial abnormalities are key factors that...

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Détails bibliographiques
Auteurs principaux: Reddy, P. Hemachandra, Manczak, Maria, Mao, Peizhong, Calkins, Marcus J., Reddy, Arubala P., Shirendeb, Ulziibat
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059092/
https://ncbi.nlm.nih.gov/pubmed/20413847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2010-100504
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