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The intersection of amyloid beta and tau at synapses in Alzheimer’s disease
The collapse of neural networks important for memory and cognition, including death of neurons and degeneration of synapses, causes the debilitating dementia associated with Alzheimer’s disease (AD). We suggest that synaptic changes are central to the disease process. Amyloid beta and tau form fibri...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4135182/ https://ncbi.nlm.nih.gov/pubmed/24853936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.05.004 |
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