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The intersection of amyloid beta and tau in glutamatergic synaptic dysfunction and collapse in Alzheimer’s disease

The synaptic connections that form between neurons during development remain plastic and able to adapt throughout the lifespan, enabling learning and memory. However, during aging and in particular in neurodegenerative diseases, synapses become dysfunctional and degenerate, contributing to dementia....

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Main Authors: Crimins, Johanna L., Pooler, Amy, Polydoro, Manuela, Luebke, Jennifer I., Spires-Jones, Tara L.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735866/
https://ncbi.nlm.nih.gov/pubmed/23528367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.arr.2013.03.002
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