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Tau - amyloid interactions in the rTgTauEC model of early Alzheimer’s disease suggest amyloid induced disruption of axonal projections and exacerbated axonal pathology

Early observations of the patterns of neurofibrillary tangles and amyloid plaques in Alzheimer’s disease suggested a hierarchical vulnerability of neurons for tangles, and a widespread nonspecific pattern of plaques that nonetheless seemed to correlate with the terminal zone of tangle bearing neuron...

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Hlavní autoři: Pooler, Amy M, Polydoro, Manuela, Wegmann, Susanne K, Pitstick, Rose, Kay, Kevin R, Sanchez, Laura, Carlson, George A, Gomez-Isla, Teresa, Albers, Mark W, Spires-Jones, Tara L, Hyman, Bradley T
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797265/
https://ncbi.nlm.nih.gov/pubmed/23839581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.23411
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