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αβγ-Synuclein triple knockout mice reveal age-dependent neuronal dysfunction

Synucleins are a vertebrate-specific family of abundant neuronal proteins. They comprise three closely related members, α-, β-, and γ-synuclein. α-Synuclein has been the focus of intense attention since mutations in it were identified as a cause for familial Parkinson's disease. Despite their d...

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Detalhes bibliográficos
Main Authors: Greten-Harrison, Becket, Polydoro, Manuela, Morimoto-Tomita, Megumi, Diao, Ling, Williams, Andrew M., Nie, Esther H., Makani, Sachin, Tian, Ning, Castillo, Pablo E., Buchman, Vladimir L., Chandra, Sreeganga S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984188/
https://ncbi.nlm.nih.gov/pubmed/20974939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005005107
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