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Double-knockout mice for α- and β-synucleins: Effect on synaptic functions

An abundant presynaptic protein, α-synuclein, is centrally involved in the pathogenesis of Parkinson's disease. However, conflicting data exist about the normal function of α-synuclein, possibly because α-synuclein is redundant with the very similar β-synuclein. To investigate the functions of...

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Detalhes bibliográficos
Main Authors: Chandra, Sreeganga, Fornai, Francesco, Kwon, Hyung-Bae, Yazdani, Umar, Atasoy, Deniz, Liu, Xinran, Hammer, Robert E., Battaglia, Giuseppe, German, Dwight C., Castillo, Pablo E., Südhof, Thomas C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC522043/
https://ncbi.nlm.nih.gov/pubmed/15465911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406283101
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