A role for Mints in transmitter release: Mint 1 knockout mice exhibit impaired GABAergic synaptic transmission

Mints (also called X11-like proteins) are adaptor proteins composed of divergent N-terminal sequences that bind to synaptic proteins such as CASK (Mint 1 only) and Munc18-1 (Mints 1 and 2) and conserved C-terminal PTB- and PDZ-domains that bind to widely distributed proteins such as APP, presenilins...

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Détails bibliographiques
Auteurs principaux: Ho, Angela, Morishita, Wade, Hammer, Robert E., Malenka, Robert C., Südhof, Thomas C.
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 2003
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC298786/
https://ncbi.nlm.nih.gov/pubmed/12547917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.252774899
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