Genetic Analysis of Mint/X11 Proteins: Essential Presynaptic Functions of a Neuronal Adaptor Protein Family

Mints/X11s are adaptor proteins composed of three isoforms: neuron-specific Mints 1 and 2, and the ubiquitously expressed Mint 3. We have now analyzed constitutive and conditional knock-out mice for all three Mints/X11s. We found that ∼80% of mice lacking both neuron-specific Mint isoforms (Mints 1...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Ho, Angela, Morishita, Wade, Atasoy, Deniz, Liu, Xinran, Tabuchi, Katsuhiko, Hammer, Robert E., Malenka, Robert C., Südhof, Thomas C.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2006
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674967/
https://ncbi.nlm.nih.gov/pubmed/17167098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2855-06.2006
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