Impaired GABAergic transmission and altered hippocampal synaptic plasticity in collybistin-deficient mice

Collybistin (Cb) is a brain-specific guanine nucleotide exchange factor that has been implicated in plasma membrane targeting of the postsynaptic scaffolding protein gephyrin found at glycinergic and GABAergic synapses. Here we show that Cb-deficient mice display a region-specific loss of postsynapt...

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Detalhes bibliográficos
Main Authors: Papadopoulos, Theofilos, Korte, Martin, Eulenburg, Volker, Kubota, Hisahiko, Retiounskaia, Marina, Harvey, Robert J, Harvey, Kirsten, O'Sullivan, Gregory A, Laube, Bodo, Hülsmann, Swen, Geiger, Jörg R P, Betz, Heinrich
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994120/
https://ncbi.nlm.nih.gov/pubmed/17690689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601819
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