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Supralinear potentiation of NR1/NR3A excitatory glycine receptors by Zn(2+) and NR1 antagonist
Coassembly of the glycine-binding NMDA receptor subunits NR1 and NR3A results in excitatory glycine receptors of low efficacy. Here, we report that micromolar concentrations of the divalent cation Zn(2+) produce a 10-fold potentiation of NR1/NR3A receptor responses, which resembles that seen upon an...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2527951/ https://ncbi.nlm.nih.gov/pubmed/18711142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805624105 |
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