Collybistin activation by GTP-TC10 enhances postsynaptic gephyrin clustering and hippocampal GABAergic neurotransmission

In many brain regions, gephyrin and GABA(A) receptor clustering at developing inhibitory synapses depends on the guanine nucleotide exchange factor collybistin (Cb). The vast majority of Cb splice variants contain an autoinhibitory src homology 3 domain, and several synaptic proteins are known to bi...

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Autores principales: Mayer, Simone, Kumar, Rohit, Jaiswal, Mamta, Soykan, Tolga, Ahmadian, Mohammad Reza, Brose, Nils, Betz, Heinrich, Rhee, Jeong-Seop, Papadopoulos, Theofilos
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2013
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870750/
https://ncbi.nlm.nih.gov/pubmed/24297911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1309078110
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