Collybistin activation by GTP-TC10 enhances postsynaptic gephyrin clustering and hippocampal GABAergic neurotransmission

In many brain regions, gephyrin and GABA(A) receptor clustering at developing inhibitory synapses depends on the guanine nucleotide exchange factor collybistin (Cb). The vast majority of Cb splice variants contain an autoinhibitory src homology 3 domain, and several synaptic proteins are known to bi...

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Detalhes bibliográficos
Main Authors: Mayer, Simone, Kumar, Rohit, Jaiswal, Mamta, Soykan, Tolga, Ahmadian, Mohammad Reza, Brose, Nils, Betz, Heinrich, Rhee, Jeong-Seop, Papadopoulos, Theofilos
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870750/
https://ncbi.nlm.nih.gov/pubmed/24297911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1309078110
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