Collybistin activation by GTP-TC10 enhances postsynaptic gephyrin clustering and hippocampal GABAergic neurotransmission

In many brain regions, gephyrin and GABA(A) receptor clustering at developing inhibitory synapses depends on the guanine nucleotide exchange factor collybistin (Cb). The vast majority of Cb splice variants contain an autoinhibitory src homology 3 domain, and several synaptic proteins are known to bi...

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Main Authors: Mayer, Simone, Kumar, Rohit, Jaiswal, Mamta, Soykan, Tolga, Ahmadian, Mohammad Reza, Brose, Nils, Betz, Heinrich, Rhee, Jeong-Seop, Papadopoulos, Theofilos
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2013
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870750/
https://ncbi.nlm.nih.gov/pubmed/24297911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1309078110
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