Endosomal Phosphatidylinositol 3-Phosphate Promotes Gephyrin Clustering and GABAergic Neurotransmission at Inhibitory Postsynapses

The formation of neuronal synapses and the dynamic regulation of their efficacy depend on the proper assembly of the postsynaptic neurotransmitter receptor apparatus. Receptor recruitment to inhibitory GABAergic postsynapses requires the scaffold protein gephyrin and the guanine nucleotide exchange...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Papadopoulos, Theofilos, Rhee, Hong Jun, Subramanian, Devaraj, Paraskevopoulou, Foteini, Mueller, Rainer, Schultz, Carsten, Brose, Nils, Rhee, Jeong-Seop, Betz, Heinrich
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5270463/
https://ncbi.nlm.nih.gov/pubmed/27941024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.771592
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