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RML prions act through Mahogunin and Attractin-independent pathways
While the conversion of the normal form of prion protein to a conformationally distinct pathogenic form is recognized to be the primary cause of prion disease, it is not clear how this leads to spongiform change, neuronal dysfunction and death. Mahogunin ring finger-1 (Mgrn1) and Attractin (Atrn) nu...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Landes Bioscience
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3904309/ https://ncbi.nlm.nih.gov/pubmed/23787699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.25054 |
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