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RML prions act through Mahogunin and Attractin-independent pathways

While the conversion of the normal form of prion protein to a conformationally distinct pathogenic form is recognized to be the primary cause of prion disease, it is not clear how this leads to spongiform change, neuronal dysfunction and death. Mahogunin ring finger-1 (Mgrn1) and Attractin (Atrn) nu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gunn, Teresa M, Carlson, George A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904309/
https://ncbi.nlm.nih.gov/pubmed/23787699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.25054
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