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Mitochondrial dysfunction precedes neurodegeneration in mahogunin (Mgrn1) mutant mice
Oxidative stress, ubiquitination defects and mitochondrial dysfunction are commonly associated with neurodegeneration. Mice lacking mahogunin ring finger-1 (MGRN1) or attractin (ATRN) develop age-dependent spongiform neurodegeneration through an unknown mechanism. It has been suggested that they act...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2007
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2128279/ https://ncbi.nlm.nih.gov/pubmed/17720281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2007.07.012 |
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