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Chronic and age-dependent effects of the spongiform neurodegeneration-associated MGRN1 E3 ubiquitin ligase on mitochondrial homeostasis

Spongiform encephalopathy is an intriguing yet poorly understood neuropathology characterized by vacuoles, demyelination, and gliosis. It is observed in patients with prion disease, primary mitochondrial disease, HIV-1 infection of the brain, and some inherited disorders, but the underlying mechanis...

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Detalhes bibliográficos
Publicado no:Mamm Genome
Main Authors: Gunn, Teresa M., Silvius, Derek, Lester, Andrew, Gibbs, Britney
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639055/
https://ncbi.nlm.nih.gov/pubmed/31089807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-019-09802-7
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