Disrupted SOX10 function causes spongiform neurodegeneration in gray tremor mice

Mice homozygous for the gray tremor (gt) mutation have a pleiotropic phenotype that includes pigmentation defects, megacolon, whole body tremors, sporadic seizures, hypo- and dysmyelination of the CNS and PNS, vacuolation of the CNS, and early death. Vacuolation similar to that caused by prions was...

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Détails bibliographiques
Publié dans:Mamm Genome
Auteurs principaux: Anderson, Sarah R., Lee, Inyoul, Ebeling, Christine, Stephenson, Dennis A., Schweitzer, Kelsey M., Baxter, David, Moon, Tara M., LaPierre, Sarah, Jaques, Benjamin, Silvius, Derek, Wegner, Michael, Hood, Leroy E., Carlson, George, Gunn, Teresa M.
Format: Artigo
Langue:Inglês
Publié: 2014
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4305468/
https://ncbi.nlm.nih.gov/pubmed/25399070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-014-9548-5
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