Disrupted SOX10 function causes spongiform neurodegeneration in gray tremor mice

Mice homozygous for the gray tremor (gt) mutation have a pleiotropic phenotype that includes pigmentation defects, megacolon, whole body tremors, sporadic seizures, hypo- and dysmyelination of the CNS and PNS, vacuolation of the CNS, and early death. Vacuolation similar to that caused by prions was...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mamm Genome
Main Authors: Anderson, Sarah R., Lee, Inyoul, Ebeling, Christine, Stephenson, Dennis A., Schweitzer, Kelsey M., Baxter, David, Moon, Tara M., LaPierre, Sarah, Jaques, Benjamin, Silvius, Derek, Wegner, Michael, Hood, Leroy E., Carlson, George, Gunn, Teresa M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4305468/
https://ncbi.nlm.nih.gov/pubmed/25399070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-014-9548-5
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados