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Abnormal regulation of TSG101 in mice with spongiform neurodegeneration

Spongiform neurodegeneration is characterized by the appearance of vacuoles throughout the central nervous system. It has many potential causes, but the underlying cellular mechanisms are not well understood. Mice lacking the E3 ubiquitin ligase Mahogunin Ring Finger-1 (MGRN1) develop age-dependent...

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Autores principales: Jiao, Jian, Sun, Kaihua, Walker, Will P., Bagher, Pooneh, Cota, Christina D., Gunn, Teresa M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier B.V. 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755232/
https://ncbi.nlm.nih.gov/pubmed/19703557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2009.08.009
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