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Evidence for sortilin modulating regional accumulation of human tau prions in transgenic mice
Misfolding of tau proteins into prions and their propagation along neural circuits are thought to result in neurodegeneration causing Alzheimer’s disease, progressive supranuclear palsy, chronic traumatic encephalopathy, and other tauopathies. Little is known about the molecular processes mediating...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5754811/ https://ncbi.nlm.nih.gov/pubmed/29203673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1717193114 |
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