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Evidence for sortilin modulating regional accumulation of human tau prions in transgenic mice
Misfolding of tau proteins into prions and their propagation along neural circuits are thought to result in neurodegeneration causing Alzheimer’s disease, progressive supranuclear palsy, chronic traumatic encephalopathy, and other tauopathies. Little is known about the molecular processes mediating...
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| Опубликовано в: : | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5754811/ https://ncbi.nlm.nih.gov/pubmed/29203673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1717193114 |
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