Wird geladen...
Persistent repression of tau in the brain using engineered zinc finger protein transcription factors
Neuronal tau reduction confers resilience against β-amyloid and tau-related neurotoxicity in vitro and in vivo. Here, we introduce a novel translational approach to lower expression of the tau gene MAPT at the transcriptional level using gene-silencing zinc finger protein transcription factors (ZFP-...
Gespeichert in:
| Veröffentlicht in: | Sci Adv |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Association for the Advancement of Science
2021
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7978433/ https://ncbi.nlm.nih.gov/pubmed/33741591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abe1611 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|