Tau reduction in the presence of amyloid-β prevents tau pathology and neuronal death in vivo

Several studies have now supported the use of a tau lowering agent as a possible therapy in the treatment of tauopathy disorders, including Alzheimer’s disease. In human Alzheimer’s disease, however, concurrent amyloid-β deposition appears to synergize and accelerate tau pathological changes. Thus f...

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Publicado en:Brain
Autores principales: DeVos, Sarah L, Corjuc, Bianca T, Commins, Caitlin, Dujardin, Simon, Bannon, Riley N, Corjuc, Diana, Moore, Benjamin D, Bennett, Rachel E, Jorfi, Mehdi, Gonzales, Jose A, Dooley, Patrick M, Roe, Allyson D, Pitstick, Rose, Irimia, Daniel, Frosch, Matthew P, Carlson, George A, Hyman, Bradley T
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2018
Materias:
Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6022692/
https://ncbi.nlm.nih.gov/pubmed/29733334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awy117
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