Characterization of TauC3 antibody and demonstration of its potential to block tau propagation

The spread of neurofibrillary tangle (NFT) pathology through the human brain is a hallmark of Alzheimer’s disease (AD), which is thought to be caused by the propagation of “seeding” competent soluble misfolded tau. “TauC3”, a C-terminally truncated form of tau that is generated by caspase-3 cleavage...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Nicholls, Samantha B., DeVos, Sarah L., Commins, Caitlin, Nobuhara, Chloe, Bennett, Rachel E., Corjuc, Diana L., Maury, Eduardo, Eftekharzadeh, Bahareh, Akingbade, Ololade, Fan, Zhanyun, Roe, Allyson D., Takeda, Shuko, Wegmann, Susanne, Hyman, Bradley T.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5439699/
https://ncbi.nlm.nih.gov/pubmed/28531180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177914
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires