Synaptic Tau Seeding Precedes Tau Pathology in Human Alzheimer's Disease Brain

Alzheimer's disease (AD) is defined by the presence of intraneuronal neurofibrillary tangles (NFTs) composed of hyperphosphorylated tau aggregates as well as extracellular amyloid-beta plaques. The presence and spread of tau pathology through the brain is classified by Braak stages and thought...

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Détails bibliographiques
Publié dans:Front Neurosci
Auteurs principaux: DeVos, Sarah L., Corjuc, Bianca T., Oakley, Derek H., Nobuhara, Chloe K., Bannon, Riley N., Chase, Alison, Commins, Caitlin, Gonzalez, Jose A., Dooley, Patrick M., Frosch, Matthew P., Hyman, Bradley T.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2018
Sujets:
Neuroscience
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928393/
https://ncbi.nlm.nih.gov/pubmed/29740275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00267
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