Synaptic Tau Seeding Precedes Tau Pathology in Human Alzheimer's Disease Brain

Alzheimer's disease (AD) is defined by the presence of intraneuronal neurofibrillary tangles (NFTs) composed of hyperphosphorylated tau aggregates as well as extracellular amyloid-beta plaques. The presence and spread of tau pathology through the brain is classified by Braak stages and thought...

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Foilsithe in:Front Neurosci
Main Authors: DeVos, Sarah L., Corjuc, Bianca T., Oakley, Derek H., Nobuhara, Chloe K., Bannon, Riley N., Chase, Alison, Commins, Caitlin, Gonzalez, Jose A., Dooley, Patrick M., Frosch, Matthew P., Hyman, Bradley T.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2018
Ábhair:
Neuroscience
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928393/
https://ncbi.nlm.nih.gov/pubmed/29740275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00267
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