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Synaptic and metabolic gene expression alterations in neurons that are recipients of proteopathic tau seeds

Recent studies suggest that misfolded tau molecules can be released, and taken up by adjacent neurons, propagating proteopathic seeds across neural systems. Yet critical to understanding whether tau propagation is relevant in pathophysiology of disease would be to learn if it alters neuronal propert...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Perez-Rando, Marta, Dujardin, Simon, Bennett, Rachel E., Commins, Caitlin, Nibhanupudy, Tara, Hyman, Bradley T.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7574323/
https://ncbi.nlm.nih.gov/pubmed/33076986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-01049-7
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