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Formation, release, and internalization of stable tau oligomers in cells

Tau is a neuronal microtubule binding protein that, in Alzheimer’s disease and other neurodegenerative diseases, can form oligomeric and large fibrillar aggregates, which deposit in neurofibrillary tangles. Tau’s physiological state of multimerization appears to vary across conditions, and a stable...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Wegmann, Susanne, Nicholls, Samantha, Takeda, Shuko, Fan, Zhanyun, Hyman, Bradley T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283951/
https://ncbi.nlm.nih.gov/pubmed/27731899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13866
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