Tau reduction in the presence of amyloid-β prevents tau pathology and neuronal death in vivo

Several studies have now supported the use of a tau lowering agent as a possible therapy in the treatment of tauopathy disorders, including Alzheimer’s disease. In human Alzheimer’s disease, however, concurrent amyloid-β deposition appears to synergize and accelerate tau pathological changes. Thus f...

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Detalhes bibliográficos
Publicado no:Brain
Main Authors: DeVos, Sarah L, Corjuc, Bianca T, Commins, Caitlin, Dujardin, Simon, Bannon, Riley N, Corjuc, Diana, Moore, Benjamin D, Bennett, Rachel E, Jorfi, Mehdi, Gonzales, Jose A, Dooley, Patrick M, Roe, Allyson D, Pitstick, Rose, Irimia, Daniel, Frosch, Matthew P, Carlson, George A, Hyman, Bradley T
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6022692/
https://ncbi.nlm.nih.gov/pubmed/29733334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awy117
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