Alzheimer's disease: synapses gone cold

Por Koffie, Robert M, Hyman, Bradley T, Spires-Jones, Tara L
Publicado em 2011

Are Tangles as Toxic as They Look?

Por Spires-Jones, Tara L., Kopeikina, Katherine J., Koffie, Robert M., de Calignon, Alix, Hyman, Bradley T.
Publicado em 2011

Nanoparticles enhance brain delivery of blood–brain barrier-impermeable probes for in vivo optical and magnetic resonance imaging

Por Koffie, Robert M., Farrar, Christian T., Saidi, Laiq-Jan, William, Christopher M., Hyman, Bradley T., Spires-Jones, Tara L.
Publicado em 2011

Tau Accumulation Causes Mitochondrial Distribution Deficits in Neurons in a Mouse Model of Tauopathy and in Human Alzheimer's Disease Brain

Por Kopeikina, Katherine J., Carlson, George A., Pitstick, Rose, Ludvigson, Adam E., Peters, Alan, Luebke, Jennifer I., Koffie, Robert M., Frosch, Matthew P., Hyman, Bradley T., Spires-Jones, Tara L.
Publicado em 2011

Gene Transfer of Human Apoe Isoforms Results in Differential Modulation of Amyloid Deposition and Neurotoxicity in Mouse Brain

Por Hudry, Eloise, Dashkoff, Jonathan, Roe, Alysson D., Takeda, Shuko, Koffie, Robert M., Hashimoto, Tadafumi, Scheel, Maria, Spires-Jones, Tara, Arbel-Ornath, Michal, Betensky, Rebecca, Davidson, Beverly L., Hyman, Bradley T.
Publicado no Sci Transl Med (2013)

Oligomeric amyloid β associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques

Por Koffie, Robert M., Meyer-Luehmann, Melanie, Hashimoto, Tadafumi, Adams, Kenneth W., Mielke, Matthew L., Garcia-Alloza, Monica, Micheva, Kristina D., Smith, Stephen J., Kim, M. Leo, Lee, Virginia M., Hyman, Bradley T., Spires-Jones, Tara L.
Publicado em 2009

Apolipoprotein E4 effects in Alzheimer’s disease are mediated by synaptotoxic oligomeric amyloid-β

Por Koffie, Robert M., Hashimoto, Tadafumi, Tai, Hwan-Ching, Kay, Kevin R., Serrano-Pozo, Alberto, Joyner, Daniel, Hou, Steven, Kopeikina, Katherine J., Frosch, Matthew P., Lee, Virginia M., Holtzman, David M., Hyman, Bradley T., Spires-Jones, Tara L.
Publicado em 2012

Studying synapses in human brain with array tomography and electron microscopy

Por Kay, Kevin R., Smith, Colin, Wright, Ann K., Serrano-Pozo, Alberto, Pooler, Amy M., Koffie, Robert, Bastin, Mark E., Bak, Thomas H., Abrahams, Sharon, Kopeikina, Katherine J., McGuone, Declan, Frosch, Matthew P., Gillingwater, Thomas H., Hyman, Bradley T., Spires-Jones, Tara L.
Publicado em 2013