New Therapeutic Avenue for ALS: Avoiding a Fatal Encounter of TDP-43 at the Mitochondria

por Hudry, Eloise
Publicado en Mol Ther (2017)

In Vivo Two Photon Imaging of Astrocytic Structure and Function in Alzheimer’s Disease

por Kelly, Patricia, Hudry, Eloise, Hou, Steven S., Bacskai, Brian J.
Publicado en Front Aging Neurosci (2018)

RNA Aptamer Probes as Optical Imaging Agents for the Detection of Amyloid Plaques

por Farrar, Christian T., William, Christopher M., Hudry, Eloise, Hashimoto, Tadafumi, Hyman, Bradley T.
Publicado 2014

Viral vectors for therapy of neurologic diseases

por Choudhury, Sourav R., Hudry, Eloise, Maguire, Casey A., Sena-Esteves, Miguel, Breakefield, Xandra O., Grandi, Paola
Publicado en Neuropharmacology (2016)

Mouse Gender Influences Brain Transduction by Intravascularly Administered AAV9

por Maguire, Casey A, Crommentuijn, Matheus HW, Mu, Dakai, Hudry, Eloise, Serrano-Pozo, Alberto, Hyman, Bradley T, Tannous, Bakhos A
Publicado 2013

Topological analyses in APP/PS1 mice reveal that astrocytes do not migrate to amyloid-β plaques

por Galea, Elena, Morrison, Will, Hudry, Eloise, Arbel-Ornath, Michal, Bacskai, Brian J., Gómez-Isla, Teresa, Stanley, H. Eugene, Hyman, Bradley T.
Publicado en Proc Natl Acad Sci U S A (2015)

Efficient Gene Transfer to the Central Nervous System by Single-Stranded Anc80L65

por Hudry, Eloise, Andres-Mateos, Eva, Lerner, Eli P., Volak, Adrienn, Cohen, Olivia, Hyman, Bradley T., Maguire, Casey A., Vandenberghe, Luk H.
Publicado en Mol Ther Methods Clin Dev (2018)

Tailored transgene expression to specific cell types in the central nervous system after peripheral injection with AAV9

por Dashkoff, Jonathan, Lerner, Eli P, Truong, Nhi, Klickstein, Jacob A, Fan, Zhanyun, Mu, Dakai, Maguire, Casey A, Hyman, Bradley T, Hudry, Eloise
Publicado en Mol Ther Methods Clin Dev (2016)

Trafficking of AAV vectors across a model of the blood-brain barrier; a comparative study of transcytosis and transduction using primary human brain endothelial cells

por Merkel, Steven F., Andrews, Allison M., Lutton, Evan M., Mu, Dakai, Hudry, Eloise, Hyman, Bradley T., Maguire, Casey A., Ramirez, Servio H.
Publicado en J Neurochem (2016)

A flow cytometry–based in vitro assay reveals that formation of apolipoprotein E (ApoE)–amyloid beta complexes depends on ApoE isoform and cell type

por Kara, Eleanna, Marks, Jordan D., Roe, Allyson D., Commins, Caitlin, Fan, Zhanyun, Calvo-Rodriguez, Maria, Wegmann, Susanne, Hudry, Eloise, Hyman, Bradley T.
Publicado en J Biol Chem (2018)

Distinct Dendritic Spine and Nuclear Phases of Calcineurin Activation after Exposure to Amyloid-β Revealed by a Novel Fluorescence Resonance Energy Transfer Assay

por Wu, Hai-Yan, Hudry, Eloise, Hashimoto, Tadafumi, Uemura, Kengo, Fan, Zhan-Yun, Berezovska, Oksana, Grosskreutz, Cynthia L., Bacskai, Brian J., Hyman, Bradley T.
Publicado 2012

A Food and Drug Administration-approved Asthma Therapeutic Agent Impacts Amyloid β in the Brain in a Transgenic Model of Alzheimer Disease

por Hori, Yukiko, Takeda, Shuko, Cho, Hansang, Wegmann, Susanne, Shoup, Timothy M., Takahashi, Kazue, Irimia, Daniel, Elmaleh, David R., Hyman, Bradley T., Hudry, Eloise
Publicado en J Biol Chem (2015)

Adeno-associated Virus Gene Therapy With Cholesterol 24-Hydroxylase Reduces the Amyloid Pathology Before or After the Onset of Amyloid Plaques in Mouse Models of Alzheimer's Diseas...

por Hudry, Eloise, Van Dam, Debby, Kulik, Wim, De Deyn, Peter P, Stet, Femke S, Ahouansou, Ornella, Benraiss, Abdellatif, Delacourte, André, Bougnères, Pierre, Aubourg, Patrick, Cartier, Nathalie
Publicado 2009

Inhibition of the NFAT Pathway Alleviates Amyloid Beta Neurotoxicity in a Mouse Model of Alzheimer's Disease

por Hudry, Eloise, Wu, Hai-Yan, Arbel-Ornath, Michal, Hashimoto, Tadafumi, Matsouaka, Roland, Fan, Zhanyun, Spires-Jones, Tara L., Betensky, Rebecca A., Bacskai, Brian J., Hyman, Bradley T.
Publicado 2012

Cromolyn Reduces Levels of the Alzheimer’s Disease-Associated Amyloid β-Protein by Promoting Microglial Phagocytosis

por Zhang, Can, Griciuc, Ana, Hudry, Eloise, Wan, Yu, Quinti, Luisa, Ward, Joseph, Forte, Angela M., Shen, Xunuo, Ran, ChongZhao, Elmaleh, David R., Tanzi, Rudolph E.
Publicado en Sci Rep (2018)

Neuronal calcineurin transcriptional targets parallel changes observed in Alzheimer disease brain

por Hopp, Sarah C., Bihlmeyer, Nathan A., Corradi, John P., Vanderburg, Charles, Cacace, Angela M., Das, Sudeshna, Clark, Timothy W., Betensky, Rebecca A., Hyman, Bradley T., Hudry, Eloise
Publicado en J Neurochem (2018)

Interstitial fluid drainage is impaired in ischemic stroke and Alzheimer’s disease mouse models

por Arbel-Ornath, Michal, Hudry, Eloise, Eikermann-Haerter, Katharina, Hou, Steven, Gregory, Julia L., Zhao, Lingzhi, Betensky, Rebecca A., Frosch, Matthew P., Greenberg, Steven M., Bacskai, Brian J.
Publicado 2013

Neuronal Cholesterol Accumulation Induced by Cyp46a1 Down-Regulation in Mouse Hippocampus Disrupts Brain Lipid Homeostasis

por Ayciriex, Sophie, Djelti, Fathia, Alves, Sandro, Regazzetti, Anne, Gaudin, Mathieu, Varin, Jennifer, Langui, Dominique, Bièche, Ivan, Hudry, Eloise, Dargère, Delphine, Aubourg, Patrick, Auzeil, Nicolas, Laprévote, Olivier, Cartier, Nathalie
Publicado en Front Mol Neurosci (2017)

Amyloid β Induces the Morphological Neurodegenerative Triad of Spine Loss, Dendritic Simplification, and Neuritic Dystrophies through Calcineurin Activation

por Wu, Hai-Yan, Hudry, Eloise, Hashimoto, Tadafumi, Kuchibhotla, Kishore, Rozkalne, Anete, Fan, Zhanyun, Spires-Jones, Tara, Xie, Hong, Arbel-Ornath, Michal, Grosskreutz, Cynthia L., Bacskai, Brian J., Hyman, Bradley T.
Publicado 2010

Gene Transfer of Human Apoe Isoforms Results in Differential Modulation of Amyloid Deposition and Neurotoxicity in Mouse Brain

por Hudry, Eloise, Dashkoff, Jonathan, Roe, Alysson D., Takeda, Shuko, Koffie, Robert M., Hashimoto, Tadafumi, Scheel, Maria, Spires-Jones, Tara, Arbel-Ornath, Michal, Betensky, Rebecca, Davidson, Beverly L., Hyman, Bradley T.
Publicado en Sci Transl Med (2013)