Inhibition of the NFAT Pathway Alleviates Amyloid Beta Neurotoxicity in a Mouse Model of Alzheimer's Disease

Amyloid β (Aβ) peptides, the main pathological species associated with Alzheimer's disease (AD), disturb intracellular calcium homeostasis, which in turn activates the calcium-dependent phosphatase calcineurin (CaN). CaN activation induced by Aβ leads to pathological morphological changes in ne...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Hudry, Eloise, Wu, Hai-Yan, Arbel-Ornath, Michal, Hashimoto, Tadafumi, Matsouaka, Roland, Fan, Zhanyun, Spires-Jones, Tara L., Betensky, Rebecca A., Bacskai, Brian J., Hyman, Bradley T.
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2012
Предметы:
Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296329/
https://ncbi.nlm.nih.gov/pubmed/22378890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6439-11.2012
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы