Topological analyses in APP/PS1 mice reveal that astrocytes do not migrate to amyloid-β plaques

Although the clustering of GFAP immunopositive astrocytes around amyloid-β plaques in Alzheimer’s disease has led to the widespread assumption that plaques attract astrocytes, recent studies suggest that astrocytes stay put in injury. Here we reexamine astrocyte migration to plaques, using quantitat...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Galea, Elena, Morrison, Will, Hudry, Eloise, Arbel-Ornath, Michal, Bacskai, Brian J., Gómez-Isla, Teresa, Stanley, H. Eugene, Hyman, Bradley T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Physical Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4697430/
https://ncbi.nlm.nih.gov/pubmed/26644572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1516779112
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