Distinct Dendritic Spine and Nuclear Phases of Calcineurin Activation after Exposure to Amyloid-β Revealed by a Novel Fluorescence Resonance Energy Transfer Assay

Calcineurin (CaN) activation is critically involved in the regulation of spine morphology in response to oligomeric amyloid-β (Aβ) as well as in synaptic plasticity in normal memory, but no existing techniques can monitor the spatiotemporal pattern of CaN activity. Here, we use a spectral fluorescen...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wu, Hai-Yan, Hudry, Eloise, Hashimoto, Tadafumi, Uemura, Kengo, Fan, Zhan-Yun, Berezovska, Oksana, Grosskreutz, Cynthia L., Bacskai, Brian J., Hyman, Bradley T.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3354533/
https://ncbi.nlm.nih.gov/pubmed/22496575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0227-12.2012
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados