Studying synapses in human brain with array tomography and electron microscopy

Postmortem studies of synapses in human brain are problematic due to the axial resolution limit of light microscopy and the difficulty preserving and analyzing ultrastructure with electron microscopy. Array tomography overcomes these problems by embedding autopsy tissue in resin and cutting ribbons...

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Bibliographische Detailangaben
Hauptverfasser: Kay, Kevin R., Smith, Colin, Wright, Ann K., Serrano-Pozo, Alberto, Pooler, Amy M., Koffie, Robert, Bastin, Mark E., Bak, Thomas H., Abrahams, Sharon, Kopeikina, Katherine J., McGuone, Declan, Frosch, Matthew P., Gillingwater, Thomas H., Hyman, Bradley T., Spires-Jones, Tara L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712649/
https://ncbi.nlm.nih.gov/pubmed/23787894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2013.078
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