Membrane association and release of wild-type and pathological tau from organotypic brain slice cultures

The spatiotemporal transmission of pathological tau in the brain is characteristic of Alzheimer's disease. Release of both soluble and abnormal tau species from healthy neurons is increased upon stimulation of neuronal activity. It is not yet understood whether the mechanisms controlling solubl...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Croft, Cara L, Wade, Matthew A, Kurbatskaya, Ksenia, Mastrandreas, Pavlina, Hughes, Martina M, Phillips, Emma C, Pooler, Amy M, Perkinton, Michael S, Hanger, Diane P, Noble, Wendy
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386587/
https://ncbi.nlm.nih.gov/pubmed/28300838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.97
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